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socramed

Word

Microgranular APL

A morphologic form of acute promyelocytic leukemia in which abnormal promyelocytes have scant visible granules and often bilobed nuclei.

Also called: microgranular morphological subtype

Unlike the classic heavily granulated form, this variant may appear nearly agranular under light microscopy. Its bilobed nuclei can help distinguish it from other acute myeloid leukemia forms. It is often associated with higher white cell counts, a feature relevant to understanding its presentation.

Card id: microgranular-apl

Sources

  • Ryan MM. Acute Promyelocytic Leukemia: A Summary. Journal of the Advanced Practitioner in Oncology, 2018, https://pmc.ncbi.nlm.nih.gov/articles/PMC6303006/

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